Wave I: 1987 – 1989
Wave II: 1987 – 1989
Wave III: 1991 – 1993
Wave IV: 1994 – 1996
Wave V: 1997 – 1998
Wave VI: 1999 -2000
Wave I: 1810 participants
Wave II: 668 participants
Wave III: 1099 participants
Wave IV: 680 participants
Wave V: 421 participants
Wave VI: 265 participants
75+
75+
The initial screening involved a nurse interview where they sought information on social factors, social network, recreational activities, socio-economic status, residence, activities of daily living, medication and home help services.
The psychological examination included administration of a test of global cognitive ability, the Mini-Mental State Examination. The screening was performed in order to identify possible dementia cases, defined as persons with MMSE scores below 24.
The nurses measured blood pressure, height, and weight, and collected samples.
All participants were interviewed by nurses, clinically examined by physicians, and assessed by psychologists.
The nurses measured blood pressure, height, and weight, collected blood samples, and assessed cognitive status with brief cognitive tasks as well as assessing physical functioning in terms of activities of daily living and instrumental activities of daily living.
The clinical examination was similar to a comprehensive somatic, neurological, and psychiatric examination usually performed in clinical practice, but was structured and defined according to various scoring criteria. The examination included family medical history with a structured family interview of all first-degree relatives, personal clinical history, retrospective cognitive assessment and clinical examination. At the end, the examiner made diagnoses of current diseases according to standardized criteria. All diagnoses were reviewed by two senior clinicians.
A family interview with a next-of-kin or a close person was carried out. The interview concerned past and current health status of the subject, as well as selective risk factors of the most common chronic neurodegenerative diseases. Information was gathered on specific topics, such as detailed occupational-life history, caregiver burden, and use of home help and home services.
The psychological examination included a comprehensive assessment of memory and other cognitive functions, including tests of episodic memory, short-term memory, verbal ability, visuospatial skill, spatial orientation, perceptual speed and executive functions.
Longitudinal
Questionnaires, cognitive measures, physical measures, biosamples
Blood pressure, height, weight, blood samples, cognitive status, physical functioning, family medical history, personal clinical history, retrospective cognitive assessment, clinical examination, occupational life history, caregiver burden, and use of home help and home services, comprehensive assessment of memory and other cognitive functions
Human aging process, special focus on dementia disorders
To expand the knowledge concerning aging and dementing disorders, as well as about the social consequences of dementia.
Psychology, Social Science, Medicine
Karolinska Institutet
Department of Neurobiology, Care Sciences and Society (NVS), H1
Prof. Laura Fratiglioni
Professor, PI of SNAC-K and KP
Aging Research Center (ARC) Department of Neurobiology, Care Sciences and Society (NVS)
Karolinska Institutet
Tel: +46 8 690 5818
laura.fratiglioni@ki.se
Maria Wahlberg
Maria.Wahlberg@ki.se
+46 (0) 8-690 58 17
Karolinska Institute
Department of Neurobiology, Care Sciences and Society (NVS), H1
http://www.kungsholmenproject.se/
Fratiglioni L, Viitanen M, Bäckman L, Sandman PO, Winblad B. Occurrence of dementia in advanced age: the study design of the Kungsholmen Project. Neuroepidemiology. 1992;11 Suppl 1:29-36.